The application for array quality is to provide guidance and valuable insights into quality control for the protein microarray. A protein microarray or also named as protein chip is a high-throughput method used to track the interactions and activities of proteins, and to determine their function, and determining function on a large scale (Melton, 2004). Its main advantage lies in the fact that large numbers of proteins can be tracked in parallel. The chip consists of a support surface such as a glass slide, nitrocellulose membrane, bead, or microtitre plate, to which an array of capture proteins is bound (Schena, 2005). Protein microarrays are rapid, automated, economical, and highly sensitive, consuming small quantities of samples and reagents (Mitchell, 2004). The high-throughput technology behind the protein microarray was relatively easy to develop since it is based on the technology developed for DNA microarrays (Hall, Ptacek and Snyder, 2012)which have become the most widely used microarrays.
-Melton, L.(2004). Protein arrays: Proteomics in multiplex. Nature. 429 (6987):pp101-107. ISSN 0028-0836
-Schena, M. (2005). Protein Microarrays. Jones & Bartlett Learning. p47. ISBN 978-0-7637-3127-4.
-Mitchell, P(2002). A perspective on protein microarrays. Nature Biotechnology. 20 (3): pp225-229. ISSN 1087-0156
-Hall, DA; Ptacek, J. and Snyder, M. (December 12, 2012). Protein Microarray Technology. Mech. Ageing Dev. 128(1):pp161-167. PMC 1828913
-Kauffmann, A.and Huber, W. (2013). Introduction: Microarray Quality Assessment with ArrayQualityMetrics, p1-7.
-(2017). DNA microarray. Retrieved 1st August, 2017, from http://www.dnamicroarray.net/.